Clomid, known by its chemical name, Clomifene, is a medication that is taken by women who are having issues with infertility. This particular medication is taken over the span of roughly five days with one pill being taken per day. This type of medication is often attributed to a higher incidence of twins. Specifically, this medication is for women who are no longer ovulating. Often, this is as a result of some type of condition or even age, however it is typically given to women who have Polycystic ovary syndrome which is often caused by having a higher amount of male androgens. This higher amount of androgens leads to issues with ovulation and even menstrual cycles. Common side effects of Clomid are hot flashes, pelvic pain, vision issues, vomiting, and in some cases ovarian cancer.
Clomid belongs to a group of drugs classified as SERM, or selective estrogen receptor modulator. It is a non-steroidal medication, which causes a release of a chemical called GnRH or Gonadotropin releasing hormone. This hormone is created in the hypothalamus in the brain.GnRH is also responsible for starting a chain reaction in which several hormones are released. Typically in females the release of GnRH begins during puberty and is largely responsible for the complex menstrual cycle that continues throughout the life of a woman until menopause. This chemical stops being released when women are pregnant.
This medication was first approved for use in the near 1967 and is recognized by the World Health Organization as one of the most critical medications in the world. The average wholesale price in the developing world ranges from slightly under one US dollar to about two dollars. A very important facet of the efficacy of this medication revolves around the specific timing of ovulation in a particular patient. It should be taken around the 5th day of the ovulation cycle and followed by frequent intercourse to increase potential pregnancy. Further more, women are monitored very closely via ultrasound from the time the last pill is taken (the 5th day). The treatment can be continued every 30 days, but it is recommended that it not be taken for more than 6 different rounds or cycles. Clomid has also been used in women who have issues with fertility that cannot be explained. I such cases it has been validated that there is success in about 6% of all cases. This medication can also be used in men, for men that are suffering from certain issues related to testosterone production. For this use it can be taken by males up to 3 times a week at about 50mg doses. It has also been used to treat gynecomastia in some males. Side effects are not all that common in patients, with fewer than 10% of all patients reporting side effects.
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